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Main Speakers/Courses
Main Speakers
- Carmen Molina- Paris (Faculty
of Mathematics and Physical Sciences,
University of Leeds, UK)
Minicourse "Stochastic birth and
death processes in immunology"
Abstract: TBA
- David Harel (Dept. of Computer
Science and Applied Mathematics
The Weizmann Institute of Science,
Israel)
Minicourse "On the Full Organism
Challenge: Or, Can we Computerize an
Elephant?"
Abstract: We show how techniques
from computer science and software
engineering can be applied beneficially
to research in the life sciences. I will
discuss the idea of comprehensive and
realistic modeling of biological
systems, where we try to understand and
analyze an entire system in detail,
utilizing in the modeling effort all
that is known about it. I will address
the motivation for such modeling and the
philosophy underlying the techniques for
carrying it out, as well as the crucial
question of when such models are to be
deemed valid, or complete. The examples
will be from among the biological
modeling efforts my group has been
involved in: T cell development, lymph
node behavior, organogenesis of the
pancreas, rat whisking, cancer tumor
formation, and various projects
regarding the C. elegans nematode.
The ultimate long-term “grand challenge”
is to produce an interactive, dynamic,
computerized model of an entire
multi-cellular organism, such as the C.
elegans, which is extremely complex
despite its small size, but well-defined
in terms of anatomy and genetics. The
sweeping potential benefits of such a
model will be discussed.
Minicourse "Modeling viral
dynamics: from ODEs to ABMs"
Abstract: In
this short course we will introduce the
concept and basics of agent based models
(ABM), following examples drawn from viral
dynamics and epidemiology. The emphasis
will be on practical issues of agent-based
models in relation to biological
processes: why and when to use ABM, how to
think about agents, events and rules. We
will also discuss implementation issues
and validation / calibration of these
models. Some existing software to code
agent-based models will be mentioned, but
not explored in detail. Participants are
encouraged to bring their own ideas for
systems they would like to model to
discuss during the tutorial.
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